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The United States recently imposed sanctions targeting Iran’s largest automobile manufacturers and key railway operators. For quantitative traders, the announcement creates immediate pricing pressure, shifts in risk premia, and new constraints on exposure to emerging‑market assets. This article translates the macro event into concrete implications for portfolio construction, factor models, and trade execution. Immediate Market Reaction and Liquidity Effects When sanctions are announced, the first observable impact is a sharp move in the prices of related securities. Iranian equities are already thinly traded, and the added regulatory risk widens bid‑ask spreads....